5 Amino 1MQ (10mg)

$74.97

5-Amino-1-methyl quinolinium (5-AMQ or 5-Amino-1MQ) is a promising NNMT inhibitor with potential applications for in vitro metabolic disease research.

SKU: 5A1MQ-10MG Categories: , Tags: , , Product ID: 6269

Description

5 Amino 1MQ Product Description

5 Amino 1MQ is a synthetic small-molecule research compound known for its selective inhibition of nicotinamide N-methyltransferase (NNMT), an enzyme closely involved in regulating cellular metabolism, methylation balance, and NAD+ availability. By modulating NNMT activity, 5-Amino-1MQ influences key biochemical pathways associated with energy production, lipid metabolism, epigenetic signaling, and mitochondrial function. This makes it a widely studied compound in preclinical models exploring metabolic health and cellular efficiency.

In laboratory research settings, 5 Amino 1MQ is primarily investigated for its ability to affect NAD+ recycling pathways and downstream metabolic signaling networks that regulate fat storage, energy utilization, and cellular adaptation.


5 Amino 1MQ Benefits

The peptide has been associated with:

  • Modulation of NAD+ metabolic pathways
  • Increased cellular energy efficiency in lab models
  • Regulation of fat metabolism and lipid storage
  • Support of mitochondrial function in preclinical studies
  • Influence on epigenetic signaling via methylation pathways
  • Interest in longevity and cellular stress-response research

5 Amino 1MQ  Effects

5 Amino 1MQ acts primarily through NNMT inhibition, which may lead to:

  • Altered nicotinamide metabolism
  • Increased NAD+ availability in cellular systems
  • Changes in methylation balance (SAM-dependent pathways)
  • Reduced adipocyte lipid accumulation in experimental models
  • Modulation of gene expression tied to metabolism and growth signaling

The 5 Amino 1MQ Dosage

Reconstitution:

  • Add 4.0 mL bacteriostatic water to the 50 mg vial
  • This creates a concentration of 12.5 mg/mL

Typical dosing range (research protocol):

  • 2.5 mg once daily (starting / tolerance phase)
  • 5 mg once daily (standard protocol)
  • Optional: 2.5 mg twice daily (split dosing / BID)

Frequency:

  • Usually once daily subcutaneous injection
  • Some protocols split into morning + evening dosing for more stable exposure

Estimated vial duration:

  • A 50 mg vial typically lasts:
    • 10–20 days, depending on whether 2.5 mg or 5 mg daily is used

5 Amino 1MQ Peptide Specifications

Property Value
Molecular Formula C10H11N2
Molecular Weight 159.21 g/mol
PubChem CID 950107
Synonyms 5-amino-1-methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZMJBCEIHNOWCMC-UHFFFAOYSA-O, STL196667
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