PEG-MGF Peptide (5mg)

$94.97

PEG-MGF Peptide (Pegylated Mechano Growth Factor) is a long-acting synthetic derivative of Mechano Growth Factor (MGF), a naturally occurring splice variant of Insulin-Like Growth Factor-1 (IGF-1). MGF is produced locally within skeletal muscle in response to mechanical stress or tissue damage, where it is believed to activate satellite cells involved in muscle repair and regeneration. Through pegylation, PEG-MGF has a significantly extended half-life compared to native MGF, making it a valuable research peptide for investigating muscle hypertrophy, tissue regeneration, and recovery mechanisms.

SKU: PMGF-5MG Categories: , Tags: , , Product ID: 6270

Description

PEG-MGF Peptide Product Description

PEG-MGF (Pegylated Mechano Growth Factor) is a modified form of Mechano Growth Factor (MGF), an isoform of IGF-1 (Insulin-Like Growth Factor-1) engineered with polyethylene glycol (PEG) to significantly extend its stability and biological activity. Standard MGF has an extremely short half-life, while pegylation allows PEG-MGF to remain active for much longer, making it a preferred option for laboratory research involving muscle regeneration, tissue repair, and cellular recovery.

Researchers continue to investigate PEG-MGF for its ability to activate satellite cells, promote muscle cell proliferation, and support regenerative processes following mechanical stress or injury. In preclinical studies, PEG-MGF has also demonstrated potential in cardiac tissue repair, bone regeneration, stem cell migration, and neuroprotection, making it an important peptide across multiple fields of regenerative medicine research.

Our PEG-MGF peptide is supplied as a highly purified lyophilized powder with no fillers, ensuring exceptional purity, stability, and consistency for laboratory applications.

PEG-MGF Peptide Specifications

Property Value
Peptide Sequence PEG-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys
Molecular Formula C121H200N42O39
Molecular Weight 2900 g/mol
CAS Number 108174-48-7
PubChem CID 178101669
Synonyms IGF-1 Ec E-peptide, MGF-E, Pegylated MGF, PEG-MGF-Ct24E, PEG Myotrophin

PEG-MGF Peptide Benefits

Current preclinical research suggests PEG-MGF may support investigations involving:

  • Muscle regeneration and satellite cell activation
  • Recovery following muscle stress or injury
  • Lean muscle growth research
  • Skeletal muscle hypertrophy mechanisms
  • Bone healing and tissue regeneration
  • Cartilage repair studies
  • Stem cell migration and differentiation
  • Cardiac tissue repair and remodeling
  • Neuroprotective and regenerative pathways
  • Cellular recovery after mechanical stress

PEG-MGF Peptide Effects

Experimental studies indicate PEG-MGF may:

  • Extend MGF biological activity through pegylation
  • Promote activation and proliferation of muscle satellite cells
  • Enhance muscle fiber repair following mechanical damage
  • Support muscle cell differentiation and fusion
  • Reduce inflammatory signaling during tissue recovery
  • Encourage stem cell recruitment to damaged tissue
  • Improve bone formation and mineralization
  • Support cartilage regeneration in tissue engineering models
  • Demonstrate cardioprotective effects following myocardial injury
  • Promote neuronal survival in neuroprotection research

PEG-MGF Peptide Dosage

Research protocols commonly reference:

  • Dose: 200–400 mcg
  • Frequency: 2–3 times per week
  • Cycle Length: 4–6 weeks

Due to PEGylation, PEG-MGF has a considerably longer half-life than standard MGF, allowing for less frequent administration in research settings.

For laboratory research use only. Not intended for human consumption or clinical use.


Why Choose Our PEG-MGF?

Our PEG-MGF is manufactured under strict quality standards and undergoes comprehensive purity testing to provide researchers with dependable and reproducible results.

Every vial features:

  • High-purity lyophilized peptide
  • No fillers or unnecessary additives
  • Excellent stability during storage
  • Consistent batch-to-batch quality
  • Ideal for metabolic, regenerative, and muscle biology research

Whether studying skeletal muscle regeneration, stem cell biology, cardiac repair, or tissue engineering, PEG-MGF remains one of the most widely researched long-acting IGF-1 derivatives available.

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