Description
N-Acetyl Selank Amidate Product Description
N-Acetyl Selank Amidate is a stabilized synthetic heptapeptide derived from the immunomodulatory peptide Selank, structurally modeled after tuftsin. This enhanced analog incorporates an N-terminal acetyl group and a C-terminal Pro-Gly-Pro amidation, significantly improving resistance to enzymatic degradation and increasing biological stability in research environments.
Designed for advanced neurological and immunological studies, the peptide is widely investigated for its potential effects on anxiety regulation, cognitive enhancement, stress adaptation, and neuroimmune signaling. Its ability to modulate key neurotransmitter systems—including GABA, serotonin, and endogenous opioid pathways—makes it a highly studied compound in neurobiology research.
This compound is supplied strictly for laboratory research use only.
N-Acetyl Selank Amidate Peptide Information
| Property | Value |
|---|---|
| Peptide Sequence | Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH₂ |
| Molecular Formula | C33H57N11O9 |
| Molecular Weight | 751.9 g/mol |
| CAS Number | 129954-34-3 |
| Synonyms | Selank, TP-7, Selanc |
N-Acetyl Selank Amidate Benefits
Current preclinical research suggests the peptide may be associated with:
- Reduced anxiety-like behavior in experimental models
- Improved cognitive performance and memory formation
- Enhanced stress resilience and adaptation
- Regulation of GABAergic neurotransmission
- Modulation of serotonin signaling pathways
- Increased brain-derived neurotrophic factor (BDNF) expression
- Immune system modulation and cytokine balance
- Improved emotional stability under chronic stress
- Neuroprotective activity in oxidative stress models
- Enhanced learning capacity and synaptic efficiency
N-Acetyl Selank Amidate Effects
Experimental findings on Selank-based peptides suggest possible effects including:
- Activation and regulation of the GABA receptor system
- Modulation of serotonin metabolism in brain regions linked to mood
- Increased levels of enkephalins through enzyme inhibition pathways
- Elevation of BDNF expression in the hippocampus
- Reduction in stress-induced corticosterone response
- Improved cognitive flexibility and learning speed
- Stabilization of emotional and behavioral responses under stress
- Regulation of immune cytokines and inflammatory markers
- Support for neuroplasticity and synaptic remodeling
- Adaptogenic response enhancement under environmental stress
N-Acetyl Selank Amidate Dosage
For laboratory research use only
Commonly referenced experimental parameters include:
- Dose Range: 250–1000 mcg per administration
- Route of Administration: Intranasal or experimental injection models
- Frequency: 1–2 times daily depending on study design
- Cycle Length: 10–30 days in most preclinical studies
- Adjustment: Dosage varies significantly depending on model and research objective
Why Researchers Study The Peptide
Researchers choose this analog because of its:
- Enhanced metabolic stability due to N-acetylation
- Increased resistance to enzymatic degradation
- Improved BBB permeability potential
- Strong anxiolytic research profile
- Broad neuroimmune signaling activity
- Extended biological duration compared to Selank
- Multi-pathway neurotransmitter modulation
- Strong preclinical behavioral research outcomes
